Prof. Itamar Raz
Prof. Raz holds an MD from Hadassah Medical School at the Hebrew University of Jerusalem where he is a professor of Internal Medicine and the Director Emeritus of the Diabetes Unit at Hadassah University Hospital.
Prof. Raz is the head of the Israel National Council of Diabetes which is responsible for formulating national policies. In addition, Prof. Raz is President of D-Cure, a non-profit organization that promotes and funds scientific research in Israel for finding a cure, prevention and better treatments for diabetes. At Hadassah, Prof. Raz has been active in basic and clinical research and is currently leading several large international outcome diabetes studies involving the heart and kidney in diabetic patients.
He has over 290 publications to his credit in professional peer-reviewed journals, lectures widely at national and international diabetes meetings and serves on several international advisory boards. In addition he serves as associate editor of The Review of Diabetic Studies, co-editor of Diabetes Metabolism Research and Reviews (DMRR) and 6 other editorial positions.
Dr. Sarah Zangen
Dr. Sarah Zangen is the director and team leader of the diabetes laboratory at the Hadassah Diabetes Unit.. Dr. Zangen is a member of the D-cure scientific board and chair of the scientist committee of the D-cure annual symposium as well as D-Cure's satellite meeting for trainees in Diabetes in Beer Sheva. The satellite meeting enhances support and promote career-development, diabetes-related research in Israel in both academia and industry as well as sharing sessions of career-experience between graduate and post-doc fellows. She is also actively involved in now actively involved OTZMA – Diabetes Care Initiative in Israel focusing on three vital needs aimed to prevent the spread of the epidemic, and the complications of diabetes in Israel.
The focus of Dr Zangen’s studies is the pathogenesis underlying β-cell failure in type 2 diabetes (T2D), seeking ways to prevent and protect the β-cells from the harmful environment. Dr Zangen performs her studies on a unique genetic rat model of nutritionally induced T2D, the Cohen diabetic rat. Her main scientific contributions: are:1) The description of an inflammatory process underlying the failure of pancreatic islet to secrete sufficient amount of insulin in diabetes, with a central role for the proinflamatory cytokine IL-1ß. 2) The identification of a direct link between islets mitochondrial function and pancreatic ß cell function and the revelation of hypothetical “critical islets COX-activity threshold” required to sustain normoglycemia. 3) mechanism of diabetes complications that the Cohen rat develops with duration of diabetes.